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A method for in vivo high resolution MRI of rat spinal cord injury
Author(s) -
Ford John C.,
Hackney David B.,
Joseph Peter M.,
Phelan Megan,
Alsop David C.,
Tabor Stacy L.,
Hand Christopher M.,
Markowitz Ronald S.,
Black Perry
Publication year - 1994
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910310216
Subject(s) - in vivo , spinal cord injury , spinal cord , magnetic resonance imaging , electromagnetic coil , artifact (error) , radiofrequency coil , biomedical engineering , medicine , nuclear medicine , nuclear magnetic resonance , radiology , physics , computer science , microbiology and biotechnology , quantum mechanics , psychiatry , biology , computer vision
We have developed an implanted radiofrequency coil to obtain high resolution in vivo MR images at 1.9 Tesla of rat spinal cords that have been injured using a standardized weight drop technique. The signal‐to‐noise ratio and motion artifact suppression of these images is superior to that achieved in earlier attempts at this field strength using an external surface coil. The high quality and spatial resolution provided by this technique afford the possibility for longitudinal studies of experimental spinal cord injury before and after treatment, as well as detailed correlation of in vivo MRI contrast, histopathological findings, and functional deficit, in a controlled setting.