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Detection of brain activation using oxygenation sensitive functional spectroscopy
Author(s) -
Hennig J.,
Emst Th.,
Speck O.,
Deuschl G.,
Feifel E.
Publication year - 1994
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910310115
Subject(s) - nuclear magnetic resonance , signal (programming language) , oxygenation , stimulation , spectroscopy , photic stimulation , signal to noise ratio (imaging) , chemistry , noise (video) , biophysics , neuroscience , physics , medicine , biology , optics , computer science , visual perception , quantum mechanics , artificial intelligence , perception , image (mathematics) , programming language
A nonwater‐suppressed localized spectroscopy experiment using the PRESS‐sequence has been used to study the signal changes of the water resonance during cortical activation. Significant effects with an effect‐to‐noise ratio up to 50:1 for a single shot experiment have been observed upon photic stimulation. The exceedingly high signal‐to‐noise ratio of the experiment was used to demonstrate signal changes as low as 0.1% after electrical stimulation of the median nerve.