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A rapid interleaved method for measuring signal intensity curves in both blood and tissue during contrast agent administration
Author(s) -
Taylor N. J.,
Rowland I. J.,
Tanner S. F.,
Leach M. O.
Publication year - 1993
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910300613
Subject(s) - projection (relational algebra) , signal (programming language) , contrast (vision) , intensity (physics) , measure (data warehouse) , resolution (logic) , orientation (vector space) , computer vision , computer science , artificial intelligence , nuclear magnetic resonance , biomedical engineering , optics , physics , mathematics , algorithm , medicine , geometry , database , programming language
A method has been developed that uses dynamic MR imaging to measure simultaneously the changes in signal intensity due to paramagnetic contrast agent in blood and tissue, using interleaved single‐angle projection and imaging sequences. The basic projection/image sequence has a projection time resolution of 50 ms and can measure rapid changes in the blood signal intensity. Variants with a tissue suppression slab have time resolutions of 57 or 75 ms. Orientation of the projection and image planes can be defined independently. This technique will facilitate functional measurements using MR contrast agents, allowing the blood input function to be determined with excellent time resolution.