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In Vivo 31 P NMR measurement of glucose‐6‐phosphate in the rat muscle after exercise
Author(s) -
Bloch G.,
Chase J. R.,
Avison M. J.,
Shulman R. G.
Publication year - 1993
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910300311
Subject(s) - in vivo , glucose 6 phosphate , metabolite , chemistry , phosphate , nuclear magnetic resonance , nuclear magnetic resonance spectroscopy , gastrocnemius muscle , inorganic phosphate , skeletal muscle , biochemistry , medicine , biology , stereochemistry , enzyme , physics , microbiology and biotechnology
Comparison of 31 P NMR spectra of the rat gastrocnemius, obtained in vivo and from PCA extracts, after electrically induced contractions, demonstrates that glucose‐6‐phosphate (G6P) is the major metabolite in the low‐field part of the PME spectral region. In vivo 31 P NMR can thus be used to measure the muscle G6P concentration after exercise.