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Incorporating lactate/lipid discrimination into a spectroscopic imaging sequence
Author(s) -
Adalsteinsson Elfar,
Spielman Daniel M.,
Wright Graham A.,
Pauly John M.,
Meyer Craig H.,
Macovski Albert
Publication year - 1993
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910300119
Subject(s) - sequence (biology) , nuclear magnetic resonance , chemistry , computer science , artificial intelligence , physics , biochemistry
A spectroscopic imaging sequence incorporating a two‐shot lactate editing method was used in two human brain studies to image lactate and NAA. The subtractive editing method allows separate images of lactate, NAA, and lipids to be collected during a single study with no SNR penalty. The sequence uses a spectral‐spatial excitation for slice selection and water suppression, and employs inversion recovery and an echo time of 136 ms for additional lipid suppression.