Measurement of  T  1  relaxation times of cardiac phosphate metabolites using BIR‐4 adiabatic RF pulses and a variable nutation method | Zendy

Sakuma Hajime | Zendy; Nelson Sarah J. | Zendy; Vigneron Daniel B. | Zendy; Hartiala Jaakko | Zendy; Higgins Charles B. | Zendy

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Measurement of T 1 relaxation times of cardiac phosphate metabolites using BIR‐4 adiabatic RF pulses and a variable nutation method

Author(s) -

Sakuma Hajime,

Nelson Sarah J.,

Vigneron Daniel B.,

Hartiala Jaakko,

Higgins Charles B.

Publication year - 1993

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.1910290517

Subject(s) - nutation , adiabatic process , nuclear magnetic resonance , chemistry , saturation (graph theory) , skeletal muscle , relaxation (psychology) , physics , analytical chemistry (journal) , mathematics , anatomy , medicine , thermodynamics , chromatography , combinatorics , astronomy

T 1 relaxation times of PCr and β‐ATP in human cardiac and skeletal muscle were evaluated using a variable nutation method. This allows T 1 measurements with a constant TR and a significant reduction in acquisition time compared with the partial saturation method. Four 1D CSI datasets were obtained using 30°, 45°, 60°, and 90° BIR‐4 adiabatic RF pulses within 40 min. The T 1 of the phosphate phantom obtained with this method agreed with values obtained with the partial saturation method. The T 1 s of PCr and β‐ATP in heart are 3.98 = 0.18 s and 1.86 ± 0.16 s (mean = SE). Our results demonstrated that T 1 values in heart and skeletal muscle are not significantly different.

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