In situ  changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain | Zendy

van Zijl Peter C. M. | Zendy; Moonen Chrit T. W. | Zendy

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In situ changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain

Author(s) -

van Zijl Peter C. M.,

Moonen Chrit T. W.

Publication year - 1993

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.1910290315

Subject(s) - inosine , hypoxanthine , ischemia , adenosine , in situ , purine , chemistry , cortex (anatomy) , cerebral cortex , nucleotide , nuclear magnetic resonance , medicine , endocrinology , biology , biochemistry , neuroscience , physics , enzyme , organic chemistry , gene

Spectral changes upon death (global ischemia) were recorded in situ in cat cerebral cortex. A rapid signal loss of 10 ± 4% in the N ‐acetyl resonance was observed (five cases), after which it remained constant for 1 h. For the first time signal changes are reported for low‐field resonances, which are assigned to adenosine/inosine and hypoxanthine.

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