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In situ changes in purine nucleotide and n‐acetyl concentrations upon inducing global ischemia in cat brain
Author(s) -
van Zijl Peter C. M.,
Moonen Chrit T. W.
Publication year - 1993
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910290315
Subject(s) - inosine , hypoxanthine , ischemia , adenosine , in situ , purine , chemistry , cortex (anatomy) , cerebral cortex , nucleotide , nuclear magnetic resonance , medicine , endocrinology , biology , biochemistry , neuroscience , physics , enzyme , organic chemistry , gene
Spectral changes upon death (global ischemia) were recorded in situ in cat cerebral cortex. A rapid signal loss of 10 ± 4% in the N ‐acetyl resonance was observed (five cases), after which it remained constant for 1 h. For the first time signal changes are reported for low‐field resonances, which are assigned to adenosine/inosine and hypoxanthine.