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Endogenous susceptibility contrast in myocardium during apnea measured using gradient recalled echo planar imaging
Author(s) -
Wendland Michael F.,
Saeed Maythem,
Lauerma Kirsi,
De Crespigny Alexander,
Moseley Michael E.,
Higgins Charles B.
Publication year - 1993
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910290220
Subject(s) - medicine , cardiology , oxygenation , intensity (physics) , apnea , gradient echo , echo planar imaging , magnetic resonance imaging , blood oxygenation , radiology , physics , quantum mechanics , functional magnetic resonance imaging
Gradient recalled echo planar imaging was used to monitor changes in myocardial and left ventricular chamber blood intensity during apnea in rats. Significant signal loss in both blood (to 62 ± 5% and 51 ± 6% of baseline) and myocardium (to 79 ± 2% and 76 ± 3% of baseline) was observed at 45 and 90 s apnea while O 2 saturation decreased from 98 ± 1% to 62 ± 7% and 36 ± 9%, respectively. These results show that myocardial intensity is modulated by alterations in blood oxygenation.