Atraumatic quantitation of cerebral perfusion in cats by  19 f magnetic resonance imaging | Zendy

Branch Craig A. | Zendy; Ewing James R. | Zendy; Helpern J. A. | Zendy; Ordidge R. J. | Zendy; Butt Shazad | Zendy; Welch K. M. A. | Zendy

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Atraumatic quantitation of cerebral perfusion in cats by 19 f magnetic resonance imaging

Author(s) -

Branch Craig A.,

Ewing James R.,

Helpern J. A.,

Ordidge R. J.,

Butt Shazad,

Welch K. M. A.

Publication year - 1992

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.1910280105

Subject(s) - normocapnia , hypercapnia , cerebral blood flow , magnetic resonance imaging , nuclear magnetic resonance , perfusion , cats , cerebral perfusion pressure , nuclear medicine , voxel , chemistry , medicine , physics , radiology , respiratory system

We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (p a CO 2 = 39 ± 4 mm Hg) and hypercapnia (p a CO 2 = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc.

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