Premium
Solid‐State 31 P NMR Spectroscopy of Bone and Bone Substitutes
Author(s) -
Marchandise Xavier,
Belgrand Patrick,
Legrand AndréPierre
Publication year - 1992
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910280102
Subject(s) - nuclear magnetic resonance spectroscopy , magic angle , phosphate , calcium , magic angle spinning , materials science , chemistry , decoupling (probability) , nuclear magnetic resonance , physics , organic chemistry , control engineering , engineering , metallurgy
Using magic angle sample spinning 31 P NMR spectroscopy, we studied NMR parameters of hydroxyapatite, calcium‐deficient hydroxyapatite, and β‐tricalcium phosphate. These data were compared to rabbit bone parameters. Rabbit bone spectrum is similar to deficient hydroxyapatite spectrum but high‐power proton decoupling did not modify its linewidth. Moreover, both bone T1 and deficient hydroxyapatite T1 were much longer than pure hydroxyapatite T1 and β‐tricalcium phosphate T1. We used these results to develop quantitative analysis of newly deposited bone inside β‐tricalcium phosphate implants in rabbit. This method made it possible to demonstrate the effect of porosity on osteoinduction of biomaterials.© 1992 Academic Press,Inc.