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T1 and t2 of ferritin at different field strengths: effect on mri
Author(s) -
Vymazal Josef,
Brooks Rodney A.,
Zak Olga,
Mcrill Connie,
Shen Cynthia,
Chiro Giovanni Di
Publication year - 1992
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910270218
Subject(s) - ferritin , nuclear magnetic resonance , magnetic field , field strength , field (mathematics) , relaxation (psychology) , serum ferritin , physics , chemistry , mathematics , neuroscience , psychology , quantum mechanics , pure mathematics , biochemistry
Nuclear magnetic relaxation times T1 and T2 were measured in ferritin solutions at field strengths from 0.04 to 1.5 T.T1 was relatively constant, but 1/T2 increased linearly with field strength, in agreement with earlier MRI observations in the monkey brain. This finding supports the theory that ferritin is responsible for T2 shortening in brain nuclei containing iron. The linear dependence of 1/T2 on magnetic field is unique and not explained by present theories of the magnetic properties of ferritin.