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Porphyrins as contrast media
Author(s) -
Nelson James A.,
Schmiedl Udo
Publication year - 1991
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910220243
Subject(s) - porphyrin , biodistribution , contrast (vision) , fluorescence , chemistry , nuclear magnetic resonance , nuclear medicine , medicine , photochemistry , computer science , biochemistry , artificial intelligence , physics , optics , in vitro
The interest in tissue distribution of variously labeled or otherwise detectable natural and synthetic porphyrins and porphyrin derivatives dates back well over 60 years. Although a considerable interest in fluorescent turnor localization and therapy dominates the history of porphyrin biodistribution studies, many investigators have evaluated the diagnostic and therapeutic characteristics of porphyrins with radioactive, radiopaque, and paramagnetic qualities. In this paper, a review of the use of porphyrins as nuclear medicine, X‐ray, and NMR contrast agents is presented. © 1991 Academic Press, Inc.