Premium
Clinical experience with contrast enhanced echo‐planar imaging of the brain
Author(s) -
Worthington B. S.,
Bullock P.,
Stehlings M.,
Gowlnad P.,
Firth J. L.,
Mansfield P.
Publication year - 1991
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910220219
Subject(s) - vascularity , medicine , contrast (vision) , brain tissue , biopsy , contrast enhancement , brain tumor , pulse (music) , radiology , magnetic resonance imaging , nuclear medicine , biomedical engineering , pathology , computer science , telecommunications , artificial intelligence , detector
The overall effects of intravenous Gd‐DTPA on tissue signal in intracranial tumors are complex depending on dose, time of administration, pulse sequence, and tissue structure. Ultrahigh speed EPI permits the kinetics of tissue enhancement in intracranial tumors to be studied during the “wash‐in” equilibrium and “wash‐out” phases. Ongoing studies employing dynamic scanning have shown it to be a valuble adjunct to a morphological study of tumors, providing an assessment of vascularity which is important in planning resction; and demonstrating areas with maximal breakdown of the blood‐brain barrier which are most suitable for stereotactic biopsy. There are grounds for anticipating that the alalysis of the temporal profil of enhancement may allow discrimination between different tumor types and provide information on factors which relate to the malignant potential of a single type. © 1991 Academic Press, Inc.