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Correction for chemical‐shift artifacts in 19 F imaging of PFOB: Simultaneous multislice imaging
Author(s) -
Lee H. K.,
Nalcioglu O.,
Buxton R. B.
Publication year - 1991
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910210105
Subject(s) - multislice , selection (genetic algorithm) , nuclear magnetic resonance , pulse sequence , computer science , spectral line , optics , physics , artificial intelligence , materials science , astronomy
One of the difficulties encountered in 19 F NMR imaging of fluorinated blood substitutes is that these compounds often exhibit complex multipeak spectra. These peaks result in chemical‐shift artifacts along the readout direction and blurred images. In addition, each peak excites a different slice (mis‐selection) when a slice selection gradient is applied during the selective rf pulse. A simultaneous multislice imaging method has been developed to solve the inherent problem of mis‐selection. The essence of this method is to use the two strongest peaks of the spectrum to excite controlled different multiple slices simultaneously, with or without a slice gap. The images corresponding to the two spectral lines are then separated from in‐and out‐of‐phase images (Dixon method). This method corrects the problem of mis‐selection and either improves the SNR or increases the number of slices over spectrally selective methods which image only one peak. © 1991 Academic Press, Inc.