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1 H spectroscopic imaging using a spectral‐spatial excitation pulse
Author(s) -
Spielman Daniel,
Meyer Craig,
Macovski Albert,
Enzmann Dieter
Publication year - 1991
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910180203
Subject(s) - excitation , voxel , nuclear magnetic resonance , pulse (music) , materials science , optics , range (aeronautics) , ranging , physics , computer science , radiology , medicine , composite material , telecommunications , quantum mechanics , detector
Excellent water suppression is required to perform in vivo 1 H spectroscopic experiments. However water suppression is difficult due to both B 0 and RF inhomogeneities. These inhomogeneities are particularly troublesome in spectroscopic imaging experiments where water suppression is required throughout some large region of interest. In this paper, we propose the use of spectral‐spatial excitation pulses for such experiments. These two‐dimensional pulses are shown to provide water suppression that is insensitive to a range of B 0 and RF variations while simultaneously providing spatial localization. Experimental results including images (with voxel volumes ranging from 3.4 to 1.5 cc) of various brain metabolites from both a normal volunteer and a patient with a metastatic lung carcinoma are presented. © 1991 Academic Press. Inc.