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Effect of oral contraception on water‐suppressed proton NMR spectra of plasma
Author(s) -
Carlier Pierre G.,
Vaesen Francis,
Gilles Raymond G.,
Fradin Elisabeth A.,
Rorive Georges L.
Publication year - 1991
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910170129
Subject(s) - nuclear magnetic resonance , proton , proton nmr , spectral line , chemistry , oral contraception , plasma , medicine , population , physics , research methodology , family planning , nuclear physics , environmental health , astronomy
Lipid linewidths were measured in the plasma proton spectra of young women. The individuals taking a contraceptive pill associating ethinyloestradiol and levonorgestrel or norethisterone were found with an average linewidth 2.5 Hz narrower than controls. As this drug regimen systematically induces an increase in plasma VLDL and a decrease in HDL/LDL ratio, our observation supports the theory that the Fossel test reflects plasma lipids abnormalities in cancer patients. © 1991 Academic Press, Inc.