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Does IVIM measure classical perfusion?
Author(s) -
Henkelman R. Mark
Publication year - 1990
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910160313
Subject(s) - intravoxel incoherent motion , measure (data warehouse) , perfusion , medicine , magnetic resonance imaging , computer science , radiology , diffusion mri , data mining
MR measurements based on motion encoding gradients provide interesting information about diffusion in tissues and have also been advanced as a way to measure tissue perfusion. This communication shows why IVIM cannot measure perfusion in the classical sense. Attempts to do so result from an unclear understanding of classical perfusion measurements and from confusion between terminal deposition (or uptake) and blood volume flow. © 1990 Academic Press, Inc.