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An in vivo NMR imaging determination of multiexponential Hahn T 2 of normal lung
Author(s) -
Shioya Sumie,
Christman Rebecca,
Ailion David C.
Publication year - 1990
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910160106
Subject(s) - lung , nuclear magnetic resonance , echo time , in vivo , nuclear medicine , spin echo , chemistry , breathing , line (geometry) , magnetic resonance imaging , physics , medicine , radiology , mathematics , anatomy , geometry , microbiology and biotechnology , biology
We describe the first in vivo imaging determination of normal lung tissue's multiexponential transverse magnetization decay. Normal spontaneously breathing rats were used for the measurements. To obtain motion‐insensitive images, we used a modified line scan imaging technique which we call the interleaved line scan (ILS). The ILS overcomes the following difficulties associated with imaging lungs: low signal‐to‐noise ratio (S/N) due to lung's low proton density and short T 2 decay, artifacts associated with cardiac and respiratory motion, and excessively long imaging times with conventional line scan techniques. Using the ILS, a 16‐line 32‐average image with an 8‐s repetition time requires 4.3 min. From a series of 16 Hahn spin‐echo images with echo times ranging from 16 to 90 ms, we obtained a two‐component T 2 decay for normal peripheml lung tissue. The measured fast and slow T 2 components were 9.5 ± 1.0 and 34 ± 5.0 ms for the right lung and 9.0 ± 1.5 and 32 ± 4.5 for the left lung. The relative magnetization for the slow T 2 component was 7.0 ± 4.5% for the right lung and 10 ± 3.0% for the left lung. © 1990 Academic Press, Inc.