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Tm(DOTP) 5− : A 23 Na + shift agent for perfused rat hearts
Author(s) -
Buster Douglas C.,
Castro M. Margarida C. A.,
Geraldes Carlos F. G. C.,
Malloy Craig R.,
Sherry A. Dean,
Siemers Timothy C.
Publication year - 1990
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910150104
Subject(s) - dysprosium , thulium , chemistry , extracellular , ion , nuclear magnetic resonance , inorganic chemistry , materials science , physics , biochemistry , optoelectronics , organic chemistry , doping
Abstract Tm(DOTP) 5− , the thulium(III) complex of 1,4,7,10‐tetraazacyclododecane N,N′,N″,N‴tetra(methylenephosphonate), is introduced as a 23 Na 1 shift agent for use in discrimination of the NMR resonances of intra‐ and extracellular 23 Na + ions in perfused rat hearts. The novel shift agent is directly compared to the widely used Dy(TTHA) 3 ‐ (dysprosium(III) triethylenetetraminehexaacetate). © 1990 Academic Press, Inc.