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Quality: quantification improvement by converting lineshapes to the lorentzian type
Author(s) -
De Graaf A. A.,
Van Dijk J. E.,
BoéE W. M. M. J.
Publication year - 1990
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910130302
Subject(s) - deconvolution , nuclear magnetic resonance , fourier transform , signal (programming language) , electromagnetic coil , transformation (genetics) , quality (philosophy) , nuclear magnetic resonance spectroscopy , computational physics , time domain , fourier analysis , spectroscopy , analytical chemistry (journal) , chemistry , physics , optics , computer science , biochemistry , quantum mechanics , chromatography , computer vision , gene , programming language
A method of time domain deconvolution, QUALITY, is described for general use in quantitative NMR spectroscopy. By division of the experimental NMR time domain signal by a reference signal, which may be obtained either in a separate experiment or via inverse Fourier transformation of an isolated single resonance in the experimental spectrum, perfect Lorentzian lineshapes can be obtained regardless of the magnetic field inhomogeneity. Experiments, both in vivo using a surface coil and in vitro using a surface coil and a HR NMR probe, show excellent performance of the method.