Triple‐quantum‐coherence‐filtered imaging of sodium ions in vivo at 4.7 tesla | Zendy

Griffey Richard H. | Zendy; Griffey Beatrice V. | Zendy; Matwiyoff Nicholas A. | Zendy

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Triple‐quantum‐coherence‐filtered imaging of sodium ions in vivo at 4.7 tesla

Author(s) -

Griffey Richard H.,

Griffey Beatrice V.,

Matwiyoff Nicholas A.

Publication year - 1990

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.1910130213

Subject(s) - ion , sodium , coherence (philosophical gambling strategy) , in vivo , chemistry , nuclear magnetic resonance , physics , microbiology and biotechnology , organic chemistry , quantum mechanics , biology

The tissue distribution of sodium ions which generate triple‐quantum coherence (TQC) in vivo is determined from images. A technique for filtering conventional sodium images, so that signal is obtained only from sodium ions which have a correlation time appropriate for producing TQC, is described. The utility of TQC‐filtered sodium images is demonstrated in a study of tumors implanted in a nude rat model, where the intensity of the TQC signal from sodium ions in the growing margin of the tumor is observed to be 200‐250% greater than that from surrounding tissue.

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