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Phospholipid bilayer contribution to 31 P NMR spectra in vivo
Author(s) -
Murphy Elizabeth J.,
Rajagopalan Bheeshma,
Brindle Kevin M.,
Radda George K.
Publication year - 1989
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910120218
Subject(s) - nuclear magnetic resonance , phospholipid , bilayer , in vivo , phosphodiester bond , chemistry , nmr spectra database , nuclear magnetic resonance spectroscopy , lipid bilayer , macromolecule , biophysics , spectral line , biochemistry , membrane , biology , rna , physics , microbiology and biotechnology , astronomy , gene
The magnetic field‐dependent phosphodiester(PDE) signal found in 31 PNMR spectra of liver and brain has been studied using saturation transfer and proton decoupling techniques. This PDE component, which accounts for as much as 45% of the signal in vivo , has been identified as primarily phospholipid bilayer with a small contribution from a motionally averaged macromolecule(S). © 1989 Academic Press, Inc.