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Diagnosis and assessment of mitral and aortic valve disease by cine‐flow magnetic resonance imaging
Author(s) -
Mitchell Leslie,
Jenkins Jeremy P. R.,
Watson Yvonne,
Rowlands Derek J.,
Isherwood Ian
Publication year - 1989
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910120205
Subject(s) - medicine , stenosis , magnetic resonance imaging , cardiology , mitral valve , aortic valve , mitral regurgitation , mitral valve stenosis , regurgitation (circulation) , radiology
Seventy‐six aortic and mitral valves, in 44 patients and 5 normal volunteers, were studied by Cine‐Flow MRI (on a 0.26‐T superconducting magnet system), utilizing compound oblique imaging planes and a Field Echo Even Rephasing sequence. All patients had had cardiac catheterization and echocardiography. All patients with valvular stenosis and aortic sclerosis ( n = 45) showed complete signal loss distal to the respective valve. Length of signal loss distal to the aortic valve in those in whom it was measured ( n = 15) allowed differentiation of aortic stenosis ( n = 9) from sclerosis ( n = 6). This also permitted grading of stenosis with highly significant correlation ( T = 0.86; P < 0.002) with pressure gradient measurement. In mitral stenosis ( n = 12) calculation of the area of signal loss distal to the mitral valve as a percentage of left ventricular cross‐sectional area showed a highly significant correlation ( T = 0.77; P = 0.001) with pressure gradient measurement. Clinically significant valvular regurgitation was graded by size and duration of signal loss proximal to the valve with concordance with angiocardiography. It is concluded that Cine‐Flow MRI has a clinical role in the diagnosis and assessment of valvular heart disease. © 1989 Academic Press, Inc.