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Conformal NMR spectroscopy: Accurate localization to noncuboidal volumes with optimum SNR
Author(s) -
Sharp Jonathan C.,
Leach Martin O.
Publication year - 1989
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910110312
Subject(s) - conformal map , spectroscopy , nuclear magnetic resonance spectroscopy , signal to noise ratio (imaging) , nuclear magnetic resonance , signal (programming language) , spectral line , computer science , materials science , analytical chemistry (journal) , chemistry , physics , optics , mathematics , mathematical analysis , chromatography , quantum mechanics , astronomy , programming language
“Conformal Spectroscopy” is a general method for the acquisition of accurately localized NMR spectra from noncuboidal regions with optimum signal‐to‐noise ratio (SNR). The method is based upon the localization of volumes defined by a number of intersecting oblique slices and may be implemented using standard imager hardware. Conformal techniques can enhance many existing localization sequences such as ISIS ( 31 P) and STEAM ( 1 H) resulting in typical SNR improvements of around 1.8, equivalent to a more than threefold reduction in acquisition time. Applications include in vivo tumor Spectroscopy.