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High‐Flux Signals and Spatial Localization in High‐Resolution 1 H Spectroscopy with Surface Coils
Author(s) -
Bourgeois D.,
Decorps M.,
Remy C.,
Benabid A. L.
Publication year - 1989
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910110216
Subject(s) - spectroscopy , flux (metallurgy) , nuclear magnetic resonance , pulse sequence , proton , resolution (logic) , pulse (music) , nuclear magnetic resonance spectroscopy , chemistry , materials science , analytical chemistry (journal) , optics , physics , nuclear physics , quantum mechanics , detector , organic chemistry , chromatography , artificial intelligence , computer science
To perform in vivo localized proton spectroscopy with water suppression, spin‐echo sequences, made of binomial pulses, are commonly used with surface coils. The frequency selective response to such a sequence is also spatially dependent, that is dependent on the sample shape and on the pulse angle adjustment. It is consequently pointed out in this paper that quantitative analysis for relative peak intensities may be strongly affected by the contribution of the high‐flux regions. In vivo proton spectroscopy of rat brain exemplifies this difficulty. It is shown that the use of selective prepulses to suppress high‐flux signals may be of poor efficiency depending on chemical shift, while the use of hard nonselective prepulses works for any chemical shift.