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Transrectal probe for 1 H MRI and 31 P MR spectroscopy of the prostate gland
Author(s) -
Narayan Perinchery,
Vigneron Daniel B.,
Jajodia Prahalad,
Anderson Charles M.,
Hedgcock Marcus W.,
Tanagho Emil A.,
James Thomas L.
Publication year - 1989
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910110209
Subject(s) - prostate , prostate gland , nuclear medicine , phosphomonoesters , nuclear magnetic resonance , prostate cancer , magnetic resonance imaging , in vivo magnetic resonance spectroscopy , medicine , radiology , physics , cancer , enzyme , inorganic phosphate
A transrectal probe for 1 H imaging and 31 P MR spectroscopy of the prostate gland is described. The probe is covered with plastic and consists of an insertional portion containing an rf coil and a handle containing a tuning and matching circuit. Using this transrectal probe, 1 H MR images and the first 31 P MR spectra of the in situ canine prostate were obtained. Serial alterations in prostate size and changes in the ratio of phosphomonoesters to ATP ratio following orchiectomy were observed. Transrectal images of the prostate appear to be superior to conventional whole body coil images in the canine. For the first time a device to obtain high signal‐to‐noise 1 H images and 31 P spectra of the in situ prostate has been constructed. This will allow the assessment oftransrectal imaging and spctroscopy as tools for medical studies of prostate pathophysiology.