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The uncommon longitudinal relaxation dispersion of human brain white matter
Author(s) -
Fischer Helmut W.,
Van Haverbeke Yves,
SchmitzFeuerhake Inge,
Muller Robert N.
Publication year - 1989
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910090319
Subject(s) - white matter , nuclear magnetic resonance , dispersion (optics) , human brain , relaxation (psychology) , magnetic resonance imaging , medicine , physics , neuroscience , biology , radiology , optics
Human brain white matter exhibits an uncommonly strong dispersion of 1/ T 1 at high fields. An additional relaxation pathway via the myelin lipids, which are not directly visible to medical NMR due to their fast T 2 decay, is proposed. Relaxation dispersion data are successfully analyzed on the basis of this model. © 1989 Academic Press, Inc.