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Rapid 31 P NMR test of liver function
Author(s) -
Thoma William J.,
Uǧurbil Kâmil
Publication year - 1988
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910080212
Subject(s) - phosphomonoesters , function (biology) , chemistry , liver function , nuclear magnetic resonance spectroscopy , biochemistry , biology , nuclear magnetic resonance , medicine , stereochemistry , physics , microbiology and biotechnology , enzyme , inorganic phosphate
The 31 P NMR spectrum of perfused rat liver was found to be dependent on the exogenous carbon available to the tissue. When pyruvate was supplied to liver initially perfused with lactate, P i decreased, phosphoenol pyruvate and phosphomonoesters increased, and nucieotide pools remained the same. It is proposed that these changes can be used to evaluate liver function. © 1988 Academic Press, Inc.
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