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Nonedited 1 H NMR lactate/ n ‐acetyl aspartate ratios and the in vivo determination of lactate concentration in brain
Author(s) -
Vink Robert,
McIntosh Tracy K.,
Faden Alan I.
Publication year - 1988
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910070111
Subject(s) - in vivo , chemistry , biology , microbiology and biotechnology
The 1 H lactate/ n ‐acetyl aspartate ratio is commonly used for the quantitation of brain lactate under pathological conditions. We demonstrate that the intensity of the lactate methyl region in water‐suppressed, nonedited 1 H spectra increases following mild brain trauma as a result of factors other than lactate accumulation. © 1988 Academic Press, Inc.