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Natural abundance 13 C NMR spectrum of glycogen in humans
Author(s) -
Jue T.,
Lohman J. A. B.,
Ordidge R. J.,
Shulman R. G.
Publication year - 1987
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910050410
Subject(s) - glycogen , in vivo , nuclear magnetic resonance spectroscopy , nuclear magnetic resonance , chemistry , biochemistry , biology , genetics , physics
In vivo NMR has focused on using 31 P and 1 H to study metabolism in humans. Comparable 31 C NMR studies have not been undertaken, presumably, because of its insensitivity. We report herein that the natural abundance 13 C signal from C 1 glycogen is observable. The ability to observe the signal opens new opportunities to noninvasively study glycogen metabolism in man. © 1987 Academic Press, Inc.