Premium
Deuterium nuclear spin relaxation in biological tissues
Author(s) -
Block Ronald E.,
Parekh Barbara C.
Publication year - 1987
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910050310
Subject(s) - deuterium , relaxation (psychology) , spin–lattice relaxation , chemistry , nuclear magnetic resonance , spin–spin relaxation , spin (aerodynamics) , analytical chemistry (journal) , condensed matter physics , nuclear physics , physics , thermodynamics , chromatography , psychology , social psychology , nuclear quadrupole resonance
The deuterium nuclear spin relaxation times have been measured in tissues taken from rats given 20% deuterium oxide in their drinking water. The spin–lattice and spin–spin relaxation times were measured at 13.7 MHz by the inversion–recovery and Carr–Purcell–Meiboom–Gill FT methods, respectively. The reciprocals of the spin–lattice (T 1 ) relaxation times were found to correlate well with those of protons in similar nondeuteriated tissues at a similar frequency (13.6 MHz) measured in a separate study. A least‐squares analysis of the data yields (I/T l )II = (0.991)(I/T 1 )D – 3.48 for five tissues (standard deviations of 0.097 for the slope and 0.383 for the intercept with a correlation coefficient of 0.986). Implications with respect to relaxation mechanisms are discussed. 0_1987 Academic Press, Inc.