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Effects of age on apparent 31 P spin–lattice relaxation times of rat brain phosphates
Author(s) -
Stolk J. A.,
Oolsen J. I.,
Alderman D. W.,
Schweizer M. P.
Publication year - 1987
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910050110
Subject(s) - spin–lattice relaxation , relaxation (psychology) , nuclear magnetic resonance , in vivo , phosphate , age groups , chemistry , endocrinology , medicine , biology , biochemistry , physics , genetics , demography , sociology , nuclear quadrupole resonance
Apparent 31 P spin–lattice relaxation times have been measured in vivo for brain phosphates in young adult, mature adult, and aged rats at 4.7 T and 35°C. Statistically significant differences were found for most phosphate species, except PCr and y‐ATP, among the three age groups, particularly between the young and mature adults. Age‐related changes in tissue composition and exchange reactions are discussed as possible contributors to these results. © 1987 Academic Press, Inc.