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Changes in nuclear magnetic resonance ( T 2 ) relaxation of limb tissue with bed rest
Author(s) -
Leblanc Adrian,
Evans Harlan,
Schonfeld Ernesto,
Ford Joseph,
Schneider Victor,
Jhingran Satish,
Johnson Philip
Publication year - 1987
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910040509
Subject(s) - rest (music) , nuclear magnetic resonance , relaxation (psychology) , magnetic resonance imaging , t2 relaxation , physics , medicine , radiology , acoustics
Abstract Bed rest is used to simulate the effects of weightlessness on human physiology. A spinecho procedure was used to image the lower leg of 15 normal male volunteers before and after 5 weeks of horizontal bedrest. In addition to noninvasively measuring muscle size changes, accurate T 2 images were produced to investigate possible relaxation time changes immediately (2–4 h) and 1–2 days after bed rest. Subcutaneous fat showed no change in T 2 , bone marrow showed a decrease, and muscle showed no change immediately after bed rest but increased 1–2 days following reambulation. © 1987 Academic Press, Inc.