1 H NMR relaxation measurements of human tissues  in situ  by spatially resolved spectroscopy | Zendy

Luyten Peter R. | Zendy; Anderson Charles M. | Zendy; den Hollander Jan A. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

1 H NMR relaxation measurements of human tissues in situ by spatially resolved spectroscopy

Author(s) -

Luyten Peter R.,

Anderson Charles M.,

den Hollander Jan A.

Publication year - 1987

Publication title -

magnetic resonance in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.696

H-Index - 225

eISSN - 1522-2594

pISSN - 0740-3194

DOI - 10.1002/mrm.1910040504

Subject(s) - relaxation (psychology) , nuclear magnetic resonance , chemistry , spectroscopy , in situ , nuclear magnetic resonance spectroscopy , adipose tissue , spin–lattice relaxation , spin–spin relaxation , spectral line , proton , analytical chemistry (journal) , physics , psychology , social psychology , biochemistry , organic chemistry , quantum mechanics , chromatography , nuclear quadrupole resonance , astronomy

Spatially resolved spectroscopy (SPARS) is a method for obtaining high‐resolution NMR spectra of well‐defined volumes of human tissues in situ . This method was combined with the Carr‐Purcell‐Meiboom‐Gill multiple‐echo sequence for T 2 , and with inversion recovery for T 1 relaxation measurements. Relaxation times obtained by SPARS were compared with standard CPMG and IR relaxation measurements and with imaging methods, using a number of relaxation phantoms. Spectroscopically resolved relaxation data of human bone marrow, muscle, and adipose tissue in situ were obtained. T 2 measurements of human adipose tissue gave different results when using single‐echo measurements rather than the CPMG method. This difference was interpreted as a J modulation effect, which shows up in fatty acid proton resonances. This J modulation effect influences the intensity of adipose tissue in routine 1 H NMR images. © 1987 Academic Press, Inc.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research