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A comparison of some gradient‐encoded volume‐selection techniques for in vivo NMR spectroscopy
Author(s) -
Galloway Graham J.,
Brereton Ian M.,
Brooks William M.,
Field James,
Irving Michael,
Baddeley Hiram,
Doddrell David M.
Publication year - 1987
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910040412
Subject(s) - imaging phantom , nuclear magnetic resonance , in vivo , nuclear magnetic resonance spectroscopy , volume (thermodynamics) , spectroscopy , materials science , chemistry , biomedical engineering , physics , optics , biology , medicine , microbiology and biotechnology , quantum mechanics
Abstract Four of the techniques proposed for in vivo volume‐selected NMR spectroscopy have been compared using a simple phantom with a large background water signal which was outside the region of interest. The methods VSE, SPACE, SPARS, and DIGGER all use pulsed field gradients for spatial encoding and were tested with a symmetric and an asymmetric phantom. SPACE was used to obtain volume‐selected 1 H NMR spectra of a human leg, demonstrating excellent discrimination between bone marrow and muscle. © 1987 Academic Press, Inc.