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Localization of unaffected spins in NMR imaging and spectroscopy (LOCUS spectroscopy)
Author(s) -
Haase Axel
Publication year - 1986
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910030619
Subject(s) - spins , spectroscopy , nuclear magnetic resonance , locus (genetics) , excitation , nuclear magnetic resonance spectroscopy , pulse sequence , spectral line , chemistry , physics , condensed matter physics , gene , biochemistry , quantum mechanics , astronomy
A new method for the localization of NMR spectra in vivo is presented. Herein a series of selective 90° pulses with different carrier frequencies in the presence of magnetic field gradients is saturating spins of unwanted regions. Only spins in the region of interest are left unaffected. The LOCUS ( loc alization of u naffected s pins) spectrum of this region is measured by a single 90° excitation pulse. The FLASH imaging sequence combined with the LOCUS technique allows the identification of the region of interest. © 1986 Academic Press, Inc.