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Ferromagnetic particles as contrast agents for magnetic resonance imaging of liver and spleen
Author(s) -
Dias M. Helena Mendonca,
Lauterbur Paul C.
Publication year - 1986
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1910030218
Subject(s) - magnetic resonance imaging , nuclear magnetic resonance , contrast (vision) , spleen , chemistry , materials science , medicine , radiology , physics , optics
Particles of magnetite, Fe 3 O 4 , accumulate preferentially in the liver and spleen after intravenous injection. Their magnetic fields drastically decrease echo intensities in spinecho proton magnetic resonance imaging sequences, as demonstrated by experiments on dogs injected with 10 mg/kg of 0.05‐μm particles. © 1986 Academic Press, Inc.