z-logo
Premium
Utilizing the diffusion‐to‐noise ratio to optimize magnetic resonance diffusion tensor acquisition strategies for improving measurements of diffusion anisotropy
Author(s) -
Armitage P.A.,
Bastin M.E.
Publication year - 2001
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.1140
Subject(s) - diffusion mri , diffusion , anisotropy , noise (video) , anisotropic diffusion , signal to noise ratio (imaging) , effective diffusion coefficient , nuclear magnetic resonance , tensor (intrinsic definition) , attenuation , fractional anisotropy , computational physics , physics , optics , magnetic resonance imaging , mathematics , computer science , artificial intelligence , image (mathematics) , medicine , radiology , thermodynamics , pure mathematics
It is well known that quantitative anisotropy measurements derived from the diffusion tensor are extremely sensitive to noise contamination. The level of noise in the diffusion tensor imaging (DTI) experiment is usually measured from some estimate of the signal‐to‐noise ratio (SNR) in the component diffusion‐weighted (DW) images. This measure is, however, highly dependent on experimental parameters, such as the diffusion attenuation b ‐value and the diffusion coefficient of the subject. Conversely, the diffusion‐to‐noise ratio (DNR), defined as the SNR of the calculated diffusion tensor trace map, provides a reliable estimate of noise contamination, which is largely independent of such parameters. In this work it is demonstrated how reliable anisotropy measurements can be obtained using an image acquisition strategy that optimizes the DNR of the DTI experiment. This acquisition scheme is shown to provide noise‐independent measurements of typical diffusion anisotropy values found in the human brain. Magn Reson Med 45:1056–1065, 2001. © 2001 Wiley‐Liss, Inc.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here