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Experimental method to eliminate frequency modulation sidebands in localized in vivo 1 H MR spectra acquired without water suppression
Author(s) -
Dong Zhengchao,
Dreher Wolfgang,
Leibfritz Dieter
Publication year - 2004
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10716
Subject(s) - sideband , in vivo , spectral line , physics , imaging phantom , modulation (music) , nuclear magnetic resonance , phase (matter) , frequency modulation , signal (programming language) , radio frequency , optics , materials science , acoustics , computer science , telecommunications , microwave , biology , microbiology and biotechnology , quantum mechanics , astronomy , programming language
An experimental method is described to eliminate frequency modulation sidebands in localized in vivo proton MR spectra acquired without water suppression. Based on the fact that the phases of the sideband artifact signals are coherent with the phases of the gradient pulses, the proposed method measures and combines signals with sequences using opposite gradients to cancel the sidebands. Factors effecting the results of the cancellation are investigated. Optimized cancellation is achieved by trimming the refocusing gradients, optimizing the spoiler gradients, or replacing the spoiler gradients with a 16‐step RF phase cycling. The performance of the method is demonstrated by phantom and in vivo experiments on the healthy rat brain. Magn Reson Med 51:602–606, 2004. © 2004 Wiley‐Liss, Inc.