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FASCINATE: A pulse sequence for simultaneous acquisition of T 2 ‐weighted and fluid‐attenuated images
Author(s) -
Takeo Kazuhiro,
Ishikawa Akihiro,
Okazaki Masato,
Kohno Satoru,
Shimizu Koji
Publication year - 2004
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10672
Subject(s) - fluid attenuated inversion recovery , pulse sequence , pulse (music) , image quality , sequence (biology) , attenuation , nuclear magnetic resonance , chemistry , computer science , physics , artificial intelligence , magnetic resonance imaging , image (mathematics) , optics , medicine , radiology , biochemistry , detector
A pulse sequence that enables simultaneous acquisition of T 2 ‐weighted and fluid‐attenuated images is presented. This sequence is referred to as FASCINATE (Fluid‐Attenuated Scan Combined with Interleaved Non‐ATtEnuation). In this new technique, the inversion pulse of conventional fast fluid‐attenuated inversion recovery (FLAIR) is replaced with a fast spin echo (FSE) acquisition that has an additional 180(y)–90(x) pulse train for driven inversion. By using appropriate scan parameters, the first part of the sequence provides T 2 ‐weighted images and the second part provides fluid‐attenuated images, thus allowing simultaneous acquisition in a single scan time comparable to that of fast FLAIR. FASCINATE was compared with conventional scanning techniques using a normal volunteer and a patient. A signal simulation was also conducted. In the human study, both T 2 ‐weighted and fluid‐attenuated images from FASCINATE showed the same image quality as conventional images, suggesting the potential for this technique to replace the combination of fast FLAIR and T 2 ‐weighted FSE for scan time reduction. Magn Reson Med 51:205–211, 2004. © 2003 Wiley‐Liss, Inc.