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A PRESTO‐SENSE sequence with alternating partial‐Fourier encoding for rapid susceptibility‐weighted 3D MRI time series
Author(s) -
Klarhöfer Markus,
Dilharreguy Bixente,
van Gelderen Peter,
Moonen Chrit T.W.
Publication year - 2003
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10599
Subject(s) - sequence (biology) , fourier transform , encoding (memory) , signal (programming language) , nuclear magnetic resonance , isotropy , computer science , pulse sequence , physics , algorithm , optics , artificial intelligence , chemistry , biochemistry , quantum mechanics , programming language
Abstract A 3D sequence for dynamic susceptibility imaging is proposed which combines echo‐shifting principles (such as PRESTO), sensitivity encoding (SENSE), and partial‐Fourier acquisition. The method uses a moderate SENSE factor of 2 and takes advantage of an alternating partial k ‐space acquisition in the “slow” phase encode direction allowing an iterative reconstruction using high‐resolution phase estimates. Offering an isotropic spatial resolution of 4 × 4 × 4 mm 3 , the novel sequence covers the whole brain including parts of the cerebellum in 0.5 sec. Its temporal signal stability is comparable to that of a full‐Fourier, full‐FOV EPI sequence having the same dynamic scan time but much less brain coverage. Initial functional MRI experiments showed consistent activation in the motor cortex with an average signal change slightly less than that of EPI. Magn Reson Med 50:830–838, 2003. © 2003 Wiley‐Liss, Inc.