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Super‐parallel MR microscope
Author(s) -
Matsuda Yoshimasa,
Utsuzawa Shin,
Kurimoto Takeaki,
Haishi Tomoyuki,
Yamazaki Yukako,
Kose Katsumi,
Anno Izumi,
Marutani Mitsuhiro
Publication year - 2003
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10515
Subject(s) - microscope , resolution (logic) , image resolution , voxel , magnetic resonance microscopy , magnet , microscopy , superconducting magnet , materials science , optics , nuclear magnetic resonance , physics , magnetic resonance imaging , computer science , artificial intelligence , spin echo , medicine , quantum mechanics , radiology
A super‐parallel MR microscope in which multiple (up to 100) samples can be imaged simultaneously at high spatial resolution is described. The system consists of a multichannel transmitter–receiver system and a gradient probe array housed in a large‐bore magnet. An eight‐channel MR microscope was constructed for verification of the system concept, and a four‐channel MR microscope was constructed for a practical application. Eight chemically fixed mouse fetuses were simultaneously imaged at the 200 μm 3 voxel resolution in a 1.5 T superconducting magnet of a whole‐body MRI, and four chemically fixed human embryos were simultaneously imaged at 120 μm 3 voxel resolution in a 2.35 T superconducting magnet. Although the spatial resolutions achieved were not strictly those of MR microscopy, the system design proposed here can be used to attain a much higher spatial resolution imaging of multiple samples, because higher magnetic field gradients can be generated at multiple positions in a homogeneous magnetic field. Magn Reson Med 50:183–189, 2003. © 2003 Wiley‐Liss, Inc.