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Error reduction and parameter optimization of the TAPIR method for fast T 1 mapping
Author(s) -
Zaitsev M.,
Steinhoff S.,
Shah N.J.
Publication year - 2003
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10478
Subject(s) - inversion (geology) , sequence (biology) , systematic error , algorithm , reduction (mathematics) , computer science , flip angle , extension (predicate logic) , random error , mathematics , statistics , geology , chemistry , geometry , medicine , paleontology , biochemistry , structural basin , magnetic resonance imaging , radiology , programming language
A methodology is presented for the reduction of both systematic and random errors in T 1 determination using TAPIR, a Look‐Locker‐based fast T 1 mapping technique. The relations between various sequence parameters were carefully investigated in order to develop recipes for choosing optimal sequence parameters. Theoretical predictions for the optimal flip angle were verified experimentally. Inversion pulse imperfections were identified as the main source of systematic errors in T 1 determination with TAPIR. An effective remedy is demonstrated which includes extension of the measurement protocol to include a special sequence for mapping the inversion efficiency itself. Magn Reson Med 49:1121–1132, 2003. © 2003 Wiley‐Liss, Inc.