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Functional perfusion imaging using continuous arterial spin labeling with separate labeling and imaging coils at 3 T
Author(s) -
Mildner Toralf,
Trampel Robert,
Möller Harald E.,
Schäfer Andreas,
Wiggins Christopher J.,
Norris David G.
Publication year - 2003
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10438
Subject(s) - site directed spin labeling , functional imaging , nuclear magnetic resonance , finger tapping , arterial spin labeling , perfusion scanning , perfusion , magnetic resonance imaging , nuclear medicine , echo planar imaging , transit time , biomedical engineering , medicine , physics , radiology , electron paramagnetic resonance , audiology , transport engineering , engineering
Functional perfusion imaging with a separate labeling coil located above the common carotid artery was demonstrated in human volunteers at 3 T. A helmet resonator and a spin‐echo echo‐planar imaging (EPI) sequence were used for imaging, and a circular surface coil of 6 cm i.d. was employed for labeling. The subjects performed a finger‐tapping task. Signal differences between the condition of finger tapping and the resting state were between −0.5% and −1.1 % among the subjects. The imaging protocol included a long post‐label delay (PLD) to reduce transit time effects. Labeling was applied for all repetitions of the functional run to reduce the sampling interval. Magn Reson Med 49:791–795, 2003. © 2003 Wiley‐Liss, Inc.