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Effects of hematocrit and oxygen saturation level on blood spin‐lattice relaxation
Author(s) -
Silvennoinen M. Johanna,
Kettunen Mikko I.,
Kauppinen Risto A.
Publication year - 2003
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10370
Subject(s) - hematocrit , oxygenation , saturation (graph theory) , hemoglobin , oxygen , chemistry , oxygen saturation , blood flow , nuclear magnetic resonance , analytical chemistry (journal) , cardiology , anesthesia , medicine , chromatography , physics , mathematics , biochemistry , organic chemistry , combinatorics
In the present study blood T 1 was determined as a function of hematocrit and oxygen saturation. T 1 showed a significant linear dependency on both of these parameters. In addition, oxygen dissolved in blood plasma in hyperoxygenated blood resulted in relaxation enhancement, comparable in size to that due to the change in oxygenation state of hemoglobin. As blood T 1 is a key factor for quantification of flow with arterial spin labeling methods, the influence of T 1 variation in the physiological range of hematocrit and oxygen saturation to flow determination is discussed. Magn Reson Med 49:568–571, 2003. © 2003 Wiley‐Liss, Inc.