Premium
Application of sensitivity‐encoded echo‐planar imaging for blood oxygen level‐dependent functional brain imaging †
Author(s) -
de Zwart Jacco A.,
van Gelderen Peter,
Kellman Peter,
Duyn Jeff H.
Publication year - 2002
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10303
Subject(s) - blood oxygen level dependent , echo planar imaging , communication noise , functional magnetic resonance imaging , nuclear magnetic resonance , sensitivity (control systems) , finger tapping , magnetic resonance imaging , functional imaging , echo time , contrast (vision) , signal (programming language) , nuclear medicine , physics , computer science , artificial intelligence , medicine , psychology , neuroscience , radiology , audiology , linguistics , philosophy , electronic engineering , engineering , programming language
Abstract The benefits of sensitivity‐encoded (SENSE) echo‐planar imaging (EPI) for functional MRI (fMRI) based on blood oxygen level‐dependent (BOLD) contrast were quantitatively investigated at 1.5 T. For experiments with 3.4 × 3.4 × 4.0 mm 3 resolution, SENSE allowed the single‐shot EPI image acquisition duration to be shortened from 24.1 to 12.4 ms, resulting in a reduced sensitivity to geometric distortions and T * 2blurring. Finger‐tapping fMRI experiments, performed on eight normal volunteers, showed an overall 18% loss in t ‐score in the activated area, which was substantially smaller than expected based on the image signal‐to‐noise ratio (SNR) and g ‐factor, but similar to the loss predicted by a model that takes physiologic noise into account. Magn Reson Med 48:1011–1020, 2002. Published 2002 Wiley‐Liss, Inc.