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Fast 31 P chemical shift imaging using SSFP methods
Author(s) -
Speck O.,
Scheffler K.,
Hennig J.
Publication year - 2002
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10279
Subject(s) - steady state free precession imaging , signal (programming language) , nuclear magnetic resonance , phosphocreatine , steady state (chemistry) , chemistry , physics , magnetic resonance imaging , computer science , medicine , radiology , programming language , energy metabolism
Steady‐state free precession (SSFP) methods have been very successful due to their high signal and short imaging times. These properties make them good candidates for applications that intrinsically suffer from low signal such as low gamma nuclei imaging. A new chemical shift imaging (CSI) technique based on the SSFP signal formation has been implemented and applied to 31 P. The signal properties of the SSFP CSI method have been evaluated and the steady‐state signal of 31 P has been measured in human muscles. Due to the T 2 and T 1 signal dependence of SSFP, the steady‐state signal mainly consists of phosphocreatine (PCr). The technique allows fast CSI acquisitions with high SNR of the PCr signal. The SNR gain for PCr over a FLASH‐based CSI method is approx. 4–5. Fast in vivo CSI of human muscle with subcentimeter resolution and high SNR is demonstrated at 2 T. Magn Reson Med 48:633–639, 2002. © 2002 Wiley‐Liss, Inc.