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High‐resolution MRI of cardiac function with projection reconstruction and steady‐state free precession
Author(s) -
Peters Dana C.,
Ennis Daniel B.,
McVeigh Elliot R.
Publication year - 2002
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10193
Subject(s) - steady state free precession imaging , papillary muscle , precession , voxel , nuclear magnetic resonance , endocardium , nuclear medicine , magnetic resonance imaging , medicine , physics , cardiology , radiology , astronomy
The purpose of this study was to investigate the trabecular structure of the endocardial wall of the living human heart, and the effect of that structure on the measurement of myocardial function using MRI. High‐resolution MR images (0.8 × 0.8 × 8 mm voxels) of cardiac function were obtained in five volunteers using a combination of undersampled projection reconstruction (PR) and steady‐state free precession (SSFP) contrast in ECG‐gated breath‐held scans. These images provide movies of cardiac function with new levels of endocardial detail. The trabecular‐papillary muscle complex, consisting of a mixture of blood and endocardial structures, is measured to constitute as much as 50% of the myocardial wall in some sectors. Myocardial wall strain measurements derived from tagged MR images show correlation between regions of trabeculae and papillary muscles and regions of high strain, leading to an overestimation of function in the lateral wall. Magn Reson Med 48:82–88, 2002. Published 2002 Wiley‐Liss, Inc.