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Volume tracking cardiac 31 P spectroscopy
Author(s) -
Kozerke Sebastian,
Schär Michael,
Lamb Hildo J.,
Boesiger Peter
Publication year - 2002
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10182
Subject(s) - imaging phantom , volume (thermodynamics) , tracking (education) , spectroscopy , nuclear medicine , computer science , biomedical engineering , nuclear magnetic resonance , chemistry , physics , medicine , psychology , pedagogy , quantum mechanics
The limited reliability and accuracy of cardiac spectroscopy have been partly attributed to effects from respiratory motion. In this work, we developed a prospective volume tracking method for respiratory motion compensation based on multiple navigator echoes and demonstrated its application in cardiac 31 P spectroscopy. The sequence consists of two 2D selective excitation pulses preceding the spectroscopic experiment to sample respiratory motion components. The navigator information is evaluated in real‐time to calculate the shift of the heart from respiration. Based on the displacement information, the spectroscopic volume and/or grid position is prospectively corrected to track the volume of interest. The method was validated with a moving compartment phantom simulating in vivo respiratory motion. With volume tracking, no signal contamination was apparent. Spectra obtained in 14 healthy volunteers were evaluated using time‐domain fitting procedures. The fitting accuracy improved consistently with volume tracking compared to data from non‐navigated reference acquisitions. Compared to other gating approaches available for spectroscopy, the current technique does not degrade the scan efficiency, thus allowing effective use of scan time. Magn Reson Med 48:380–384, 2002. © 2002 Wiley‐Liss, Inc.