Premium
High‐resolution isotropic 3D diffusion tensor imaging of the human brain
Author(s) -
Golay Xavier,
Jiang Hangyi,
van Zijl Peter C.M.,
Mori Susumu
Publication year - 2002
Publication title -
magnetic resonance in medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.696
H-Index - 225
eISSN - 1522-2594
pISSN - 0740-3194
DOI - 10.1002/mrm.10143
Subject(s) - diffusion mri , white matter , multislice , nuclear magnetic resonance , human brain , brainstem , physics , sensitivity (control systems) , neuroscience , high resolution , signal (programming language) , diffusion imaging , magnetic resonance imaging , computer science , medicine , psychology , radiology , geology , remote sensing , electronic engineering , engineering , programming language
High‐resolution cardiac‐gated 3D diffusion tensor imaging (3D‐DTI) is demonstrated in vivo for several areas of the human brain. Anatomical mapping of subcortical white matter (WM), as well as definition and identification of major WM bundles from the brainstem were performed in humans for the first time using this technique. Improved intrinsic signal‐to‐noise ratio (SNR) and relatively reduced sensitivity to physiological motion (e.g., brain pulsations) with respect to cardiac‐gated multislice acquisition are demonstrated. The advantages and weaknesses of this approach are discussed. Magn Reson Med 47:837–843, 2002. © 2002 Wiley‐Liss, Inc.